NanoCelle® - Next Generation Drug Delivery

At Medlab, we are constantly pushing boundaries to deliver life-changing medicines, uncovering new ways of targeting disease and creating the next generation of therapeutics. With its application of nanotechnology Medlab’s innovative NanoCelle® medicine delivery platform is designed to overcome the limitations posed by current conventional delivery systems – regardless of the active pharmaceutical ingredient (API).

Watch the video to learn more about NanoCelle®
 


Simple, Viable, Scalable and Validated Production


Our research into nanoparticles has spanned more than two decades and offers the exciting opportunity for the creation of not only the next generation of new or improved drug delivery systems but also diagnostics, anti-microbial techniques, forms of cell repair and more.

NanoCelle® offers a market-ready and commercially viable delivery solution with patent protection in Australia, New Zealand, Canada, UK and Europe until 2036:

  • Stability: up to two years at room temperature
  • Scalable: able to be scaled up for high-volume production – 50 mL to 1000 litres
  • Administration and dosing flexibility: oromucosal (oro-buccal/sublingual) sprays, intranasal sprays, dermal and transdermal formulations, topical lotions, oral gel capsules and liquids, and adsorption onto solid carriers
  • Simple processing: easy single-day production using standard pharmaceutical liquid manufacturing equipment
  • Validated: the uniform pattern in nanoparticle form is independently validated by leading industry and academic partners to ensure standardisation.

Medlab partners with Particle Technology Labs Ltd a premier particle technology research company and trusted advisor to the world’s industry leaders, including pharmaceuticals, manufacturing, defence, agriculture, food and beverage industries as well as the public sector and scientific organisations.

Partnering Opportunities

NanoCelle significantly increase bioavailability

NanoCelle allows drug delivery directly into the bloodstream


NanoCelle® – The science behind the technology


The NanoCelle® delivery platform allows passive diffusion of APIs directly into the bloodstream via oral-buccal, sublingual, intranasal and transdermal or topical delivery.

NanoCelle® – The science behind the technology

These convenient non-traditional NanoCelle® administration routes:

  • Are easily performed
  • Ideal for people who have difficulties swallowing, experience gastrointestinal complications or poor liver function which can limit absorption, or fear needles
  • Provide alternatives to traditional oral administration without compromising compliance.

How NanoCelle® works

How NanoCelle® works

NanoCelle® technology creates water-soluble nanoparticles that optimise delivery regardless of the original solubility characteristics of API payload:

  • Sub-micron sized finished product particles – ranging from 5 nm to 90 nm
  • API payload is contained within an inner hydrophobic core surrounded by an outer hydrophilic shell
  • Provides delivery of water- or lipid-soluble APIs

The versatility of NanoCelle® technology means that nanoparticles can be designed to release the API payload in response to specific environmental triggers.


NanoCelle® applications

NanoCelle® has potential medical and international applications such as small and high molecular weight.

Medlab has a portfolio of ongoing research and commercial endeavours creating a pipeline of applications to develop ourselves or take forward with partners. We offer our nanotechnology expertise in a range of areas including pharmaceuticals, cosmetics, dietary supplements and textiles from concept to manufactured end product.


NanoCelle® in medicine

NanoCelle® research has been applied across a wide range of small and large molecules and is currently being utilised in Medlab’s own medicines, nutritional products and a range of off-patent drugs with a growing patent portfolio.

Find out more about how NanoCelle® is being used with cannabinoids, small molecules and biologic products in the Medlab pipeline program.

NanoCelle® in medicine

NanoCelle® and textiles

Medlab has now successfully demonstrated that NanoCelle® technology can be used to absorb nanoparticles onto a textile. The payload compound remains inert until a ‘trigger’ causes the effective release of the compound with the intended action.

The next-generation in smart clothing
NanoCelle® technology offers strong potential in functional textiles, with a broad spectrum of applications for military textiles, first responders and activewear.

Military textiles – with increased protection and performance for deployed soldiers

NanoCelle® has the potential to enhance a soldier’s ability to withstand or repel harsh conflict conditions, smartly administer life-saving medications, dress wounds, and enable greater care outcomes for wounded service people on the battlefield. NanoCelle® offers unique military potential in functional textiles, with a broad spectrum of potential uses, including:

  • UV blocking
  • Medication release, e.g. coagulant, antibiotic, anti-toxin
  • Wound-dressing fabrics, patches
  • Photonic sensing, e.g. temperature, humidity, pressure
  • Repellence, including water, oil, blood, urine, etc.
  • Fabric strength enhancement
  • Fire retardance
  • Fabric cooling
  • Anti-static effect, including clothes and gloves.
First responders – with advanced life-saving tools for first responders
Smart activewear – with enhancements for injury reduction and muscle fatigue

NanoCelle® offers a range of potential applications in activewear products to boost the performance of athletes and aid in recovery, including:

  • Skin and muscle fibre repair
  • Fabric cooling
  • UV blocking
  • Wound-dressing fabrics, patches
  • Photonic sensing, e.g. temperature, humidity, pressure.